Effect of 40℃ 3% sodium chloride solution nasal irrigation combined with fluticasone nasal spray in the treatment of allergic rhinitis

Objective:To investigate the effects of 40℃ 3% sodium chloride solution nasal irrigation combined with fluticasone nasal spray in the treatment of allergic rhinitis(AR).Methods:The clinical data of 160 patients with AR were retrospectively analyzed.The patients were randomly divided into the control group and treatment group(80 cases each group).The control group and treatment group were treated with fluticasone propionate nasal spray and 40℃ 3% sodium chloride solution nasal irrigation, respectively.The symptoms, signs and general condition in two groups were evaluated after 8 weeks of treatment.Results:The effective rate in treatment group was higher than that in control group(P<0.05), the nasal obstruction, rhinorrhea and sneeze in treatment group were less than those in control group(P<0.01), and the symptom differences of rhinocnesmus and throat itching between two groups were not statistically significant(P>0.05).The nasal mucosal edema and nasal secretion in treatment group were less than those in control group(P<0.05 and P<0.01), but the differences of the nasal mucosa pale and conjunctival congestion between two groups were not statistically significant(P>0.05).Conclusions:The treatment of AR with 40℃ 3% sodium chloride solution nasal irrigation combined with fluticasone propionate nasal spray is safe and effective.