Effect of goal-direct therapy on the perioperative cardiac enzyme in ectopic pregnancy patients with hemorrhagic shock

Objective: To evaluate the effects of goal-direct therapy(GDT) on perioperative cardiac enzyme in ectopic pregnancy patients with hemorrhagic shock. Methods: Fifty ectopic pregnancy patients with hemorrhagic shock scheduled by operation were divided into the goal-direct therapy(GDT) group(group A, 25 cases) and conventional infusion treatment group(group B, 25 cases) by random number table method. The hemodynamics change, serum creatine kinase, isoenzyme of creatine kinase and troponin T in two groups were recorded before operation(T₀), at the start of operation(T₁), after 30 min(T₂), 1h(T₃), 2h(T₄) and at the end of operation(T₅), and the data were analyzed. Results: The levels of serum creatine kinase, isoenzyme of creatine kinase and troponin T in group A were lower than those in group B from T₂ to T₅(P<0.05 to P<0.01). The levels of HR and MAP from T₁ to T₃ and CVP at T₂ in group A were higher than those in group B(P<0.01). Conclusions: The treatment of ectopic pregnancy patients with hemorrhagic shock with GDT can increase the effective capacity load of myocardium, and has a certain myocardial protection.