Effect of transuretheral plasmakinetic resection in the treatment of benign prostatic hyperplasia with the prostate volume more than 80 mL in 45 cases

Objective: To explore the safety and effectiveness of transuretheral plasmakinetic resection of prostate(PKRP) in the treatment of benign prostatic hyperplasia(BPH) with the prostate volume more than 80 mL.Methods: Forty-five BPH cases with the prostate volume more than 80 mL and functional capacity more than 4 METs were treated with PKRP.The central venous pressure(CVP) was monitored during the operation,the 20 to 40 mg of furosemide was intravenously administrated in the patients with CVP more than 3 cm H₂O or normal value.The operation time,the levels of pre- and post-operation hemoglobin,hematocrit and serum sodium,and the maximum flow rate(Qmax),international prostate symptom score(IPSS),quality of life(QOL) and complication after 3,6 and 12 months of operation were analyzed.Results: The operations in 45 cases with the prostate volume more than 80 mL were successful,no case was transferred to open surgery and transfused.The operation time of patients was(92.56±29.69)min.The differences of the levels of sodium,hemoglobin and hematocrit between before and after operation were statistically significant(P>0.05).Compared with theses before operation,the Qmax,IPSS and QOL after 3,6 and 12 months of operation were significantly improved(P<0.01).Conclusions: In the case of functional capacity more than 4 METs,getting perioperative ready and monitoring intraoperative central venous pressure,the PKRP in the treatment of BPH with the prostate volume more than 80 mL is safe and effective.