Effect of rosuvastatin on the lung function and quality of life in stable COPD patients

Objective: To investigate the effects of oral administration of rosuvastain on the lung function and quality of life in stable chronic obstructive pulmonary disease(COPD) patients.Methods: Eighty-eight patients with COPD were randomly divided into the observation group and the control group(44 cases each group).The control group were treated with conventional therapy,and the observation group were treated with 20 mg rosuvastain by oral,once a day for 6 months based on conventional therapy.The first second forced expiratory volume(FEV1) and ratio of FEV1 to forced vital capacity(FVC) in patients were determined before treatment and after 1 and 6 months of treatment,which was used to evaluate the lung function of patients.The quality of life of patients was evaluated using the CAT scale.Results: The FEV1 level after 6 months of treatment,and ratio of FEV1 to FVC after 1 and 6 months of treatment in two groups were higher than higher those before treatment(P<0.01),and the ratio of FEV1 to FVC after 6 months of treatment in observation group was higher than that in control group.The CAT score in observation group after 1 and 6 months of treatment and score of CAT in control group after 1 mouth of 6 months were lower than those before treatment(P<0.01),and the scores of CAT in observation group affter 1 and 6 months of treatment were lower than that in control group(P<0.01).Conclusions: The rosuvastain can improve the lung function and quality of life in patients with COPD,the curative effect of which is distinct,and worthy of popularization and application.