Experimental study of Qing Ying Hua Yu particle in the treatment of thrombophlebitis

Objective: To explore the mechanism of Qing Ying Hua Yu particle in the treatment of phlebitis of rabbit.Methods: The infusion phlebitis rabbit model induced by vinoerbline was established.The animals were divided into the Qing Ying Hua Yu group,Tong Sai Mai group,model group and blank group.The related indicators in 4 groups were observed.Results: The adjusting the coagulation function and reducing the fibrinogen in Qing Ying Hua Yu group were better than those in Tong Sai Mai group(P<0.05 to P<0.01).The difference of thrombogenesis between Qing Ying Hua Yu group and Tong Sai Mai group,the difference of inflammatory cell infiltration between Qing Ying Hua Yu group and model group,and the difference of drop of epithelial cells between Qing Ying Hua Yu group and blank group were statistically significant(P<0.01).Conclusions: Qing Ying Hua Yu particle can treat the superficial thrombophlebitis by repairing endothelial cells,controlling inflammation and organizing thrombus.