Meta-analysis of the Dachengqi decoction in the treatment of the early postoperative inflammatory intestinal obstruction

Objective: To evaluate the clinical effects of Dachengqi decoction combined with Western medicine in the treatment of early postoperative inflammatory intestinal obstruction.Methods: The related literatures were searched from CNKI,CBM and Wanfang database,and statistically analyzed using RevMan5.2 software.Results: Twenty-one studies and 1 037 patients were selected.The results of Meta-analysis showed that the cure rate of the Dachengqi decoction combined with Western medicine in the treatment of early postoperative inflammatory intestinal obstruction was higher than that of Western medicineOR=5.16,95%CI(3.30 to 8.06),P<0.01.The recovery time of anus exhaust in the patients treated with the Dachengqi decoction combined with Western medicine was shorter than that in the patients treated with Western medicineWMD=-1.50,95%CI(-1.95 to -1.15),P<0.01.The hospitalization time in the patients treated with the Dachengqi decoction combined with Western medicine was shorter than that in the patients treated with Western medicineWMD=-3.45,95%CI(-4.55 to -2.35),P<0.01.The serum level of interleukin-6 in the patients treated with the Dachengqi decoction combined with Western medicine was lower than that in the patients treated with Western medicineSMD=-6.01,95%CI(-9.19 to 2.84),P<0.01.The difference of the serum level of tumor necrosis factor-α between two groups was not statistically significantSMD=-1.87,95%CI(-4.00 to 0.27),P>0.05.Conclusions: The treatment of early postoperative inflammatory intestinal obstruction with Dachengqi decoction combined with Western medicine can effectively improve the cure rate,shorten the recovery time of of anus exhaust and hospitalization time,and decrease the serum level of interleukin-6 of patients.