Comparative analysis of the clinical effects between different repairs in nasal septum perforation

Objective:To observe the clinical effects between three kinds of repairs of nasal septum perforation and nasal ventilation function change.Methods:Fifty-four patients with nasal septum perforation were divided into A,B and C groups.The A,B and C groups were treated with autologous temporal fascia and perpendicular plate of ethmoid bone sandwich technique,autograft with pedicle nasal mucoperiosteal flap repair method,and single pedicle sticky periosteum or perichondrium flip flap combined with free temporalis myofascial flap repair method,respectively.The treatment effects and postoperative nasal ventilation function in three groups were observed.Results:The intraoperative blood loss and operation time in group B were significantly lower than those in A and C groups(P<0.05 to P<0.01).The mucosal injury area and wound healing time in B and C groups were significantly better than those in group A(P<0.05).The wound healing time in group C was shorter than that in group B(P<0.05),and the differences of the healing stage between the three groups were not statistically significant(P>0.05).The minimal cross-sectional area of nasal cavity in group C at postoperative 3 months and 1 year were significantly higher than that in A and B groups.Conclusions:The clinical effect of the single pedicle sticky periosteum or perichondrium flip flap combined with free temporal fascia flap repair method in the treatment of nasal septum perforation is good,which in improving the nasal ventilation function is better than that in autologous temporal fascia and perpendicular plate of ethmoid bone sandwich technique,and autograft with pedicle nasal mucoperiosteal flap repair method.