Clinical effect of the Bushen Kangfengshi Recipe combined with western medicine in the treatment of the secondary osteoporosis in patients with rheumatoid arthritis

Objective: To observe the curative effects of the Bushen Kangfengshi Recipe combined with western medicine in the treatment of the secondary osteoporosis in patients with rheumatoid arthritis.Methods: One hundred and twenty-two rheumatoid arthritis patients with secondary osteoporosis were randomly divided into the observation group and control group(61 cases each group).The control group was treated with methotrexate and leflunomide,and the observation group was additionally treated with Bushen Kangfengshi Recipe based on the control group for 6 months.The morning stiffness time,index of joint swelling,joint tenderness and joint function,blood calcium level,platelet(PLT) count,erythrocyte sedimentation rate(ESR),rheumatoid factor(RF),c-reactive protein(CRP) level,lumbar spine,femoral neck,Ward triangle and greater trochanter bone density between two groups were compared.The clinical effects in two groups were evaluated after treatment.Results: Compared with before treatment,the morning stiffness time,joint tenderness index,joint swelling index and joint function in two groups were obviously improved after treatment(P<0.01),and the improvement degree of which in observation group was significantly better than that in control group(P<0.01).Compared with before treatment,the PLT,ESR,RF and CRP in two groups were obviously improved after treatment(P<0.01).The blood calcium level in observation group was significantly improved after treatment(P<0.01),and the improvement degree of which in observation group was significantly better than that in control group(P<0.01).The total effective rate in observation group(91.8%) was significantly higher than that in control group(75.4%)(P<0.05).Compared with before treatment and control group,the lumbar spine,femoral neck,Ward triangle and greater trochanter bone density in observation group were significantly improved after treatment(P<0.01).Conclusions: The curative effects of the Bushen Kangfengshi Recipe combined with western medicine in the treatment of the secondary osteoporosis in patients with rheumatoid arthritis are good,which can significantly improve the clinical symptoms and bone metabolism of patients.