Analysis of the postpartum glucose metabolism outcome and its related factors in patients with gestational diabetes mellitus

Objective:To explore the postpartum glucose metabolism outcome and its influencing factors in patients with gestational diabetes mellitus(GDM) for providing the reference to prevent the abnormal postpartum glucose metabolism.Methods:The clinical data of 931 patients with GDM were collected.The postpartum 6 to 12 weeks glucose metabolism information was investigated,and the related factors of abnormal postpartum glucose metabolism were analyzed.Results:Among 931 patients,308 cases(33.08%) with abnormal glucose metabolism were found after 6 to 12 weeks of delivery,which included 35 cases of diabetes mellitus,14 cases of impaired fasting glucose(IFG),7 cases of IFG complicated with impaired glucose tolerance(IGT) and 252 cases of impaired glucose tolerance(IGT).The levels of the gestational fasthg plasma glucose(FPG),2h plasma glucose(2hPG),and 3h plasma glucose(3hPG) in GDM patients with abnormal postpartum glucose metabolism were higher than those in normal group(P<0.01),but the neonatal body weight was lower than that in normal group(P<0.01).The univariate analysis showed the gestational FPG,2hPG,3hPG and neonatal body weight were the influencing factors of the GDM patients with abnormal postpartum glucose metabolism.The multivariate analysis showed that the gestational FPG,2hPG and 3hPG were the independent risk factor of abnormal postpartum glucose metabolism.The higher the value of FPG(OR=3.528),2hPG(OR=1.579) and 3hPG(OR=1.655) were,the higher the risk of abnormal postpartum glucose metabolism was.Conclusions:The postpartum abnormal glucose metabolism can be found in partial GDM patients,which is related to the result of OGTT.The pertinent following up administration and preventing measures should be developed.