Research of correlations between red blood cell distribution width and acute cerebral infarction and short-term prognosis

Objective:To evaluate the correlations between red blood cell distribution width(RDW)and acute cerebral infarction and short-term(3 months) prognosis.Methods:Ninety patients with acute cerebral infarction and 30 healthy people were divided into cerebral infarction group and control group,respectively.The RDW in all cases were detected.The acute cerebral infarction group were divided into high RDW group(RDW>13.5%) and low RDW group(RDW ≤ 13.5%) according to the median of RDW.The National Institutes of Health Stroke Scale(NIHSS) scores in acute cerebral infarction patients when admitted to the hospital were evaluated,the functional recovery of patients after 3 months of acute cerebral infarction was evaluated using the modified Rankin scale(mRS).The acute cerebral infarction patients were divided into the good prognosis group(mRS ≤ 2 points) and poor prognosis group(mRS>2 points) according to the mRS scores.Results:The RDW in cerebral infarction group was significantly higher than that in control group(P<0.01).The NIHSS score in high RDW group was significantly higher than that in low RDW group(P<0.01).The RDW was significantly positive correlation with the NIHSS score(P<0.01).The RDW in poor prognosis group was significantly higher than that in good prognosis group(P<0.01).The area under the receiver operating characteristic(ROC) curve was 0.703 according to the RDW to identify the acute cerebral infarction,the optimal cut-off value,sensitivity and specificity were 12.9%,66.67% and 73.33%,respectively.The AUC of the short-term adverse prognosis was 0.831 according to the RDW to predict the acute cerebral infarction,and the critical point was more than 13.5%,the sensitivity and specificity were 88.46% and 71.87%,respectively.Conclusions:The RDW may be an important parameter in the diagnosis of acute cerebral infarction,which has a certain clinical reference value in assessing the severity and short-time prognosis of patients.