Correlation analysis between mean platelet volume/platelet ratio and systemic lupus erythematosus activity

Objective:To investigate the correlation between mean platelet volume/platelet ratio(MPR) and systemic lupus erythematosus(SLE).Methods:Thirty-six SLE patients and 40 age-and gender-matched medical examiner were divided into the SLE group and control group,respectively.The MPV,MPR,SLE disease activity index(SLEDAI) and erythrocyte sedimentation rate(ESR) were retrospectively analyzed.Results:The levels of MPV and MPR in SLE group were higher than those in control group(P<0.05 and P<0.01).The ESR was positively correlated with MPV and MPR(P<0.01 and P<0.05).The MPR was positively correlated with SLEDAI(P<0.01),and the MPV was not obviously correlated with SLEDAI(P>0.05).Conclusions:MPR may be an useful index in estimating the SLE activity.