Analysis of the correlation between arrhythmia and heart rate variability, and postoperative cardiac function in children with congenital heart disease before and after intervention therapy

Objective: To investigate the correlations between arrhythmia and heart rate variability(HRV),and postoperative cardiac function in children with congenital heart disease(CHD) before and after intervention therapy.Methods: Seventy-nine CHD children treated with interventional occlusion were divided into the atrial septal defect group(ASD group,26 cases),ventricular septal defect(VSD group,39 cases),and patent ductus arteriosus(PDA group,14 cases) according to the disease.The changes of arrhythmia and HRV between three groups were compared before and after interventional therapy,and the correlation between postoperative cardiac function and HRV time domain indexes was analyzed.Results: Among 79 cases,the different types of arrhythmia of 40 cases(50.63%) in 28 patients(35.44%) were detected,and the ratios of atrial premature beat(<30 times/h),room premature beat(Lown's level 1) and incomplete right bundle branch block were 32.50%,22.5% and 12.50%,respectively.After operation,54 cases(68.35%) in 17 patients(21.52%) with different types arrhythmia were detected,which increased compared with before operation(P<0.05).The detection rate of different types arrhythmia in VSD group was the highest(53.70%),which was significantly higher than that before operation(P<0.05).The SDANN in PDA group during the postoperative 24 h was significantly higher than that with before operation(P<0.05).The SDANN,R-R and SDNN in ASD and VSD group during the postoperative 24 h were significantly higher than those before operation(P<0.05 to P<0.01).The levels of SDANN,R-R and SDNN in children with grade Ⅰ and Ⅱ Killip cardiac function were significantly higher than those in children with grade Ⅲ and Ⅳ Killip cardiac function(P<0.01).The level of ASDNN in children with grade Ⅰ Killip cardiac function was significantly higher than that in children with grade Ⅲ and Ⅳ Killip cardiac function during the postoperative 24 h(P<0.05).The rMSSD in children with grade Ⅰ and Ⅱ Killip cardiac function were significantly higher than that in children with grade Ⅳ Killip cardiac function during(P<0.05).HRV time domain index was significantly positively correlated with cardiac function classification(P<0.05).Conclusions: After intervention treatment,the new arrhythmia and HRV elevation in CHD children may occur,which is related to the heart function of patients.