Effect comparsion between microwave ablation guided by ultrasound and open surgery in the treatment of hyroid nodules

Objective:To compare the operative effect between microwave ablation guided by ultrasound and traditional open surgery in treating thyroid nodules.Methods:A total of 100 cases with benign thyroid nodules were divided into the microwave ablation group(50 cases,treated with microwave ablation guided by ultrasound) and traditional group(50 cases,treated with traditional open surgery) according to patients' intention.The operation time,intraoperative blood loss,postoperative hospitalization time,incidence rate of complications,cosmetic effect,and serum levels of interleukin-6(IL-6),C-reactive protein(CRP) and tumor necrosis factor-α(TNF-α) after 12 h of surgery were compared between two groups.Results:The cosmetic effect in microwave ablation group was better than that in traditional group.The operation time,intraoperative blood loss,postoperative hospitalization time in microwave ablation group were significantly less than those in traditional group(P<0.01).The difference of the incidence rate of complication between microwave ablation group(4.00%) and traditional group(12.00%) was not statistically significant(P>0.05).After 12 h of operation,the levels of IL-6,CRP and TNF-α in microwave ablation group were significantly lower than those in traditional group(P<0.01).Conclusions:Compared with traditional operation,the microwave ablation guided by ultrasound in treating thyroid nodules has short time,minimal invasion,rapid recovery,good curative effect and no scar,which has strong clinical application value.