Study on the correlation between glycosylated hemoglobin and epicardial adipose tissue thickness in CHD patients

Objective:To explore the relationship between glycosylated hemoglobin level and epicardial adipose tissue thickness(EATT) in coronary heart disease(CHD) patients.Methods:A total of 510 patients with CHD were examined using coronary arteriography,and divided into the CHD group and control group according to the results of coronary arteriography.The EATT in anterior descending branch,cyclotron branch and right coronary artery were measured according to multilayer spiral cardiac CT scan imaging,the total thickness of the three(Total EATT) was calculated,and the lycosylated hemoglobin were measured.Results:The mean glycosylated hemoglobin level in CHD group(6.2±1.2)mmol/L was significantly higher than that in control group(5.8±0.8)mmol/L)(P<0.001).The Total EATT in CHD group(26.33±7.8)mm was significantly higher than that in control group(22.72±6.3)mm)(P<0.01).The glycosylated hemoglobin level was positively correlated with the Total EATT(r=0.207,P<0.01).Multivariate regression analysis showed that the glycosylated hemoglobin level was an independent predictor of Total EATT(P<0.01).Conclusions:The glycosylated hemoglobin level increasing is positively correlated with EATT in CHD patients.