Effect of the thyroid hormone level on the prognosis of patients with acute respiratory distress syndrome

Objective:To investigate the effects of triiodothyronine 3(T3) level on the prognosis of patients with acute respiratory distress syndrome(ARDS).Methods:Forty patients with ARDS were divided into the survival group and death group according to the hospitalization 30 days outcome.The age,APACHE Ⅱ score,levels of Calcitonin,hypersensitive c-reactive protein,white blood cell count,pH,lactic acid,FT3,free thyroxine and thyroid-stimulating hormone between two groups were compared,and the influencing factors of hospitalization 30 days outcome were analyzed.Results:The level of T3 in death group was significantly lower than that in survival group on the first day of ARDS diagnosis (P<0.05).The level of T3 on the first day in survival group was significantly lower than that on the third day(P<0.01),and no obvious change in T₃ level was found in death group(P>0.05).The results of multivariate logistic regression analysis showed that the FT3 level and APACHEⅡ score were the influencing factors of hospitalization 30 days outcome(P<0.05).Conclusions:The detection of T3 level can help to assess the severity of ARDS,and predict the prognosis of patients.