Efficacy analysis of percutaneous biliary stent combined with ¹²⁵Ⅰ intracavitary implantation in the treatment of malignant obstructive jaundice

ObjectiveTo analyze the clinical efficacy of percutaneous biliary stent combined with ¹²⁵Ⅰ intracavitary implantation in the treatment of malignant obstructive jaundice.

MethodsA total of 137 malignant obstructive jaundice patients with inoperability were treated with percutaneous biliary stent implantation.According to the implantation of ¹²⁵Ⅰ particle, the patients were divided into observation group(75 cases) and control group(62 cases).The tumor volume and liver function before and after treatment, stent patency time and survival time between two groups were analyzed and compared.

ResultsCompared with the control group, the maximum and minimum diameter of tumor significantly decreased, and the liver function indexes were significantly improved in observation group at postoperative 3 months(P < 0.01).The stent patency rates in observation group at postoperative 9, 12 and 15 months were significantly better than those in control group(P < 0.01).The 1-year survival rate in observation group and control group was 72.0% and 33.9%, respectively, and the difference of which was statistically significant(P < 0.01).

ConclusionsPercutaneous biliary stent combined with ¹²⁵Ⅰ intracavitary implantation can inhibit the tumor growth, improve liver function and prolong the stent patency and survival time, and the treatment effect of which is superior to that of simple transcutaneous biliary stent implantation.