Effect of low dose propofol maintenance anesthesia on the hemodynamics and recovery agitation after vocal cord polypectomy

ObjectiveTo investigate and analyze the effects of low dose propofol maintenance anesthesia on hemodynamics and recovery agitation in patients with vocal cord polypectomy.

MethodsOne hundred patients scheduled by vocal cord polypectomy were divided into the observation group and control group according to random number table method(50 cases each group).The control group was treated with routine anesthesia, and the observation group was treated with 0.5 mg/kg propofol by intravenous injection.The gender, age, body weight, operation time and intraoperative bleeding in two groups were observed, heart rate(HR), mean arterial pressure(MAP) and oxygen saturation(SpO₂) before and after operation, agitation score, recovery during recovery period (including the recovery time of spontaneous breathing, eye opening, extubation and incidence rate of agitation) in two groups were analyzed.

ResultsHR and MAP of patients in two groups were significantly lower than those before operation(P < 0.01), HR and MAP were significantly higher at extubation, HR and MAP in observation group were significantly lower than those in control group(P < 0.01), HR and MAP in two groups were significantly lower 30 minutes after extubation(P < 0.01), SpO₂ in two groups was significantly lower at extubation(P < 0.01), and recovered 30 minutes after extubation(P < 0.01).At different time after operation, the restlessness score of the observation group was lower than that of control group(P < 0.05 to P < 0.01).There was a significant difference in the restlessness score between the two groups at different time after operation(P < 0.01).The restlessness score at extubation was significantly higher than that at awakening and 30 minutes after extubation(P < 0.01).There was no significant difference in extubation time between the two groups(P > 0.05).The recovery time of spontaneous breathing and the opening time of eyes in the observation group were significantly longer than those in the control group(P < 0.01), and the incidence of restlessness in the observation group was significantly lower than that in the control group(P < 0.01).

ConclusionsThe low dose propofol maintenance anesthesia can effectively reduce the fluctuation of hemodynamics and recovery agitation, and improve the breathing recovery time and opening eye time in patients with vocal cord polypectomy.