ObjectiveTo investigate the abnormal anatomy of gastroesophageal reflux using gastric ultrasound contrast, and provide the imaging evidence for the clinical diagnosis and treatment.
MethodsForty-eight patients with gastroesophageal reflux and 51 healthy people were divided into the observation group and control group, respectively.The His angle and length of the esophagus in two groups were detected using contrast-enhanced ultrasonography of gastric filling and gastrointestinal meal barium, respectively, and which was compared between two groups.The relationship between the His angle and esophageal length of abdomen was investigated, and the diagnostic value of which in gastroesophageal reflux was evaluated.
ResultsThe differences of the diagnositic results of His angle and abdominal esophageal length between two methods were not statistically significant(P>0.05).The results of ultrasonic examination showed that the esophagus length of abdominal section and His angle in observation group were lower and more than those in control group, respectively(P < 0.01).Taking 59.03° as the cut-off value, the sensitivity and specificity of His angle in the diagnosis of gastroesophageal reflux were 80.00% and 85.71%, respectively, and the area under ROC curve was 0.886.Taking 2.743 cm as the cut-off value, the sensitivity and specificity of abdominal esophageal length in the diagnosis of gastroesophageal reflux were 72.86% and 74.29%, respectively, and the ROC curve was 0.800.The abdominal esophageal length detected by ultrasound was negatively correlated with His angle(r=-0.681, P < 0.01).
ConclusionsThe contrast-enhanced ultrasonography of gastric filling can accurately evaluate the His angle of patients with gastroesophageal reflux, and is safe and non-invasive operation, which has a certain diagnostic value for gastroesophageal reflux disease.
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