Analysis of the risk factor of the ventilator-associated pneumonia in ICU

ObjectiveTo analyze the risk factors of ventilator-associated pneumonia(VAP) in intensive care unit(ICU), and provide scientific evidence for prevention and treatment of VAP.

MethodsA total of 112 patients treated with mechanical ventilation > 48 h were divided into the VAP group(42 cases) and non-VAP group(70 cases) according to clinical diagnosis.The age, sex, state of consciousness, underlying disease, hospitalization time, and mechanical ventilation between two groups were compared.

ResultsThe differences of the tracheostomy, enteral nutrition, aspiration frequence, air pressure therapy, early rehabilitation, hospitalization time, mechanical ventilation time and antimicrobial drug use between two groups were statistically significant(P < 0.01).Multivariate logistic regression analysis showed that the tracheotomy, long hospitalization time, long time of mechanical ventilation, antimicrobial drug combination were the independent risk factor of VAP.

ConclusionsVAP can be caused by several high-risk factors.Taking the targeted preventive measures, strengthening the VAP risk factor monitoring and strict implementing the sterile operation system can reduce the incidence of VAP.