Comparative study of the effect of NIPPV and oxygen hood on the transition tripper in preterm infants after mechanical ventilation

ObjectiveTo compare the effects between nasal synchronized intermittent positive pressure ventilation(SNIPPV) and oxygen hood on the transition tripper in preterm infants after mechanical ventilation.

MethodsForty preterm infants with pediatric respiratory distress syndrome were randomly divided into the observation group and control group(20 cases each group).The observation group and control group were treated with SNIPPV and oxygen hood, respectively.The levels of PaCO₂ and PaO₂ between two groups at different time-points after weaning were compared.The oxygen therapy time, hospitalization time, incidence of apnea, success rate of weaning, and incidence rate of complications between two groups were compared.

ResultsThe levels of PaO₂ in observation group after 12 and 24 h after weaning were higher than that in control group(P < 0.05 and P < 0.01), and the levels of PaCO₂ in observation group were lower than that in control group(P < 0.05).The differences of the levels of PaO₂ and PaCO₂ between two groups after 48 h of weaning were not statistically significant(P > 0.05).The oxygen therapy time and hospitalization time in observation group were significantly shorter than those in control group(P < 0.01).The success rate of weaning in observation group(85.0%) was higher than that in control group(P < 0.05).The incidence rate of apnea in observation group(20.0%) was lower than that in control group(50.0%)(P < 0.05).The differences of the incidence rate of complications between two groups was not statistically significant(P > 0.05).

ConclusionsThe application of SNIPPV in transition tripper in preterm infants after mechanical ventilation can decrease the incidence rate of apnea, effectively shorten the oxygen therapy time and hospitalization time, and improve the oxygenation and success rate of weaning.