Value of ABCD score in predicting early risk of cerebral ischemic stroke after transient ischemic attack

ObjectiveTo investigate the clinical value of three kinds of ABCD score in predicting the risk of new cerebral ischemic stroke within 7 days after transient ischemic attack(TIA)in Chinese.

MethodsThe scores in 150 patients with TIA were evaluated using ABCD2, ABCD3 and ABCD3-Ⅰ score within 48 h of admission, and the patients were divided into the low, medium and high risk groups according to the score.According to the onset of new ischemic stroke within 7 days after TIA, 150 patients were divided into the new ischemic stroke group(50 patients) and non-new ischemic stroke(100 patients).Three kinds of scores between two groups were compared.The number of patients with secondary cerebral infarction in the low, medium and high risk groups within 7 days after TIA was recorded.

ResultsCompared with the non-new ischemic stroke group, the scores of three kinds of ABCD score significantly increased in new ischemic stroke group, and the difference of which was statistically significant(P < 0.05 to P < 0.01).Except the score of ABCD2, with the increasing of the scores of ABCD3 and ABCD3-Ⅰ, the incidence rate of secondary cerebral infarction increased continuously within 7 days after TIA(P < 0.01).The area under the ROC curve showed that the predictive AUC value of three kinds of ABCD score was 0.67, 0.84 and 0.91 within 7 days after TIA, respectively, and the differences of those were statistically significant(P < 0.01).The degrees of accuracy of ABCD3-Ⅰ and ABCD3 score in predicting the secondary cerebral infarction within 7 days after TIA were better than those of ABCD3 and ABCD2 score, respectively(P < 0.01).

ConclusionsABCD2, ABCD3 and ABCD3-Ⅰ score can predict the secondary cerebral infarction within 7 days after TIA, and the higher the score, the higher the secondary cerebral infarction risk within 7 days after TIA is.The prediction accuracy of ABCD3-Ⅰ score is the highest.