Effect of pulmonary protective ventilation combined with pulmonary reextension on pulmonary function and oxygen partial pressure in perioperative patients treated with laparotomy under general anesthesia

ObjectiveTo and analyze the effects of pulmonary protective ventilation combined with pulmonary reextension on pulmonary function and oxygen partial pressure (PaO₂) during the perioperative period in patients treated with laparotomy under general anesthesia.

MethodsSixty patients scheduled by laparotomy under general anesthesia from March 2015 to March 2017 were randomly divided into the observation group and control group(30 cases each group).The observation group was treated with lung protective ventilation strategy(tidal volume for 6 mL/kg) combined with pulmonary resuscitation, and the control group was treated with the standard ventilation volume (tidal volume for 8 mL/kg).The airway pressure, respiratory frequency, pulse oxygen saturation(SpO₂), PaO₂, end-expiratory partial pressure of carbon dioxide(P_ETCO₂) and incidence rate of complications between two groups were compared.

ResultsThe respiratory frequency, airway pressure and P_ETCO₂ in observation group during operation were higher than those in control group(P < 0.01), and the levels of SpO₂ and PaO₂ in observation group after operation were higher than those in control group(P < 0.01).The levels of postoperative lung function indexes in two groups decreased compared with before operation, and the predicted value percentage of FEV and FEV1, FVC and FVC, and FEV1/FVC in observation group were better than those in control group(P < 0.05 to P < 0.01).The incidence rate in observation group and control group was 6.67% and 3.33%, respectively, and the difference of which was not statistically significant(P>0.05).

ConclusionsThe pulmonary protective ventilation combined with pulmonary reextension is helpful to improve perioperative pulmonary function and PaO₂ in patients treated with laparotomy under general anesthesia and has safety, which is worthy of popularization and application.