Correlation between the serum level of vitamin D and thyroid function in type 2 diabetes mellitus patients

ObjectiveTo explore the correlation between the serum level of vitamin D and thyroid function, clinical indicators in type 2 diabetes mellitus(T2DM) patients.

MethodsAccording to the serum level of 25 hydroxyvitamin25(OH)D, 151 patients with T2DM were divided into the normal group(≥ 30 ng/mL), insufficient group(20~30 ng/mL), deficient group(10~20 ng/mL) and severely deficient group(< 10 ng/mL).The relationship between the serum level of 25(OH)D and clinical indicators, thyroid function was compared.

ResultsThe proportion of patients with serum vitamin D deficiency was 89.40% among the T2DM patients.The differences of the correlations of serum levels of vitamin D with FT3, TSH and TGAb and TMAb among four groups were statistically significant(P < 0.05).Logistic regression analyses indicated that the serum level of vitamin D was negatively correlated with TSH in T2DM patients.

ConclusionsThe serum vitamin D deficiency is negatively correlated with TSH in patients with T2DM.Supplementing vitamin D and monitoring thyroid function should be considered in patients with T2DM.