Serum levels of hypersensitive troponin T, hypersensitive C-reactive protein and homocysteine in patients with acute coronary syndrome, and its clinical significance

ObjectiveTo explore the relationships between the serum levels of hypersensitive troponin T(hs-cTnT), hypersensitive C-reactive protein(hs-CRP), homocysteine(Acy) and degree of coronary artery disease in patients with acute coronary syndrome(ACS).

MethodsOne hundred and twenty patients with ACS were set as the observation group, which included the unstable angina pectoris group(UAP group, 60 cases) and acute myocardial infarction(AMI group, 60 cases), and 60 physical examiners were set as the control group at the same time.The serum levels of hs-cTnT, hs-CRP and HCY in observation group were detected after 24 h of admission, and compared with the control group.The correlations of serum levels of hs-cTnT, hs-CRP and HCY with degrees of coronary artery disease were analyzed.

ResultsThe differences of the serum levels of hs-cTnT, hs-CRP and HCY among three groups were statistically significant(P < 0.01), the above three indexes in AMI group were significantly higher than those in UAP group and control group(P < 0.01), and the above three indexes in UAP group were significantly higher than those in control group(P < 0.01).With the disease degree aggravating, the serum levels of hs-cTnT, hs-CRP and HCY increased gradually, and the difference of which was statistically significant(P < 0.01).The level of hs-cTnT was positively correlated with that of hs-CRP(P < 0.01), the level of hs-cTnT was positively correlated with that of HCY(P < 0.01), and the level of hs-CRP was positively correlated with that of HCY(P < 0.01).

ConclusionsThe serum levels of hs-cTnT, hs-CRP and HCY have certain value in the clinical diagnosis of ACS, and clinical guiding significance in identifying the degree and range of coronary artery lesions, which is worthy of clinical promotion and application.