Effect of adequate hydration combined with refined care on the prevention of contrast-induced nephropathy after PCI

ObjectiveTo investigate the effects of adequate hydration combined with refined care on the prevention of contrast-induced nephropathy(CIN) after percutaneous coronary intervention(PCI).

MethodsA total of 62 patients treated with PCI were randomly divided into the intervention group(31 cases) and control group(31 cases).The control group was treated with routine drinking water and nursing after operation, and the intervention group was treated with sufficient drinking water after 3 hours of operation combined with refined care.The levels of serum creatinine(sCr) and cystatin C(Cys-C) in two groups were detected before operation and after 12 h to 72 h of operation.The treatment effects and patients' satisfaction in two groups were observed.

ResultsThe differences of the levels of sCr and Cys-C in intervention group among before operation and postoperative 5 time-points were not statistically significant(P>0.05), and the differences of the levels of sCr and Cys-C in control group among all time-points were statistically significant(P < 0.05).The level of sCr after 72 h of PCI was higher than that before operation and after 12 h and 24 h of PCI, and the level of Cys-C after 72 h of operation was higher than that before PCI(P < 0.05 to P < 0.01).The incidence rates of CIN, stomach upset and urinary retention in intervention group were lower than those in control group(P < 0.05 to P < 0.01).The satisfaction rate in intervention group was higher than that in control group(P < 0.05).

ConclusionsThe adequate hydration combined with refined care intervention can prevent the CIN occurrence, stomach upset and urinary retention, improve the satisfaction after PCI, and greatly reduce the postoperative discomfort of patients.