Study on the correlation between Helicobacter pylori infection and homocysteine level in cerebral infarction patients

ObjectiveTo explore the correlation between common high-risk factors of cerebral infarction and Helicobacter pylori(HP) infection.

MethodsThe common high-risk factors and HP infection in patients with cerebral infarction were retrospectively analyzed, and their relationship was studied.

ResultsThe difference of the positive rate of HP-IgG antibody between cerebral infarction group and non-cerebral infarction group was not statistically significant(P>0.05).The homocys-zing level in HP-IgG positive group was higher than that in HP-IgG negative group(P < 0.05).After adjusting the factors of gender, age, diabetes, hypertension, smoking and alcohol consumption, the positive HP-IgG was the independent influencing factor of high level of homocys-zing(OR=5.968, 95% CI:1.506~23.647, P < 0.05).

ConclusionsThere is no significant difference in HP infection rate between cerebral infarction patients and general population.The HP in cerebral infarction patients complicated with HP infection has no significant effect on blood lipid level.However, HP infection may increase the risk of cerebral infarction by increasing the serum level of homocys-zing.