Clinical study on contrast agent extravasation in acute ischemic stroke patients after machinery thrombectomy

ObjectiveTo explore the reasons of contrast agent extravasation in acute ischemic stroke patients after mechanical thrombectomy, and analyze its correlation with prognosis.

MethodsForty acute large vessel occlusion patients with successful re-opened of offending vessels after thrombectomy were divided into the non-contrast agent extravasation group, exudative contrast agent extravasation group and hemorrhagic contrast agent extravasation group.The from onset to revascularization time(OTR), from puncture to revascularization time(PTR), number of intraoperative pulling bolt, volume of extravasated contrast agent, time of absorption, postoperative 24 h score of national institute of health stroke scale(NIHSS) and postoperative 3 months score of modified Rankin scale(mRS) among three groups were compared.

ResultsThe differences of the OTR, PTR, 24 h NIHSS score, ASPECT score and 3-month mRS score were statistically significant among three groups(P < 0.01).The volume of contrast agent exudation in exudation group was lower than that in bleeding group(P < 0.01), while the difference of the total absorption time of contrast agent, number of successful pulling bolt recanalization between two groups were not statistically significant(P>0.05).

ConclusionsShortening the length of hospital stay and outpatient of patients with ischemic stroke, knowing surgical technique and reducing the number of pulling plug can reduce the probability of postoperative contrast agent extravasation and cerebral hemorrhage transformation, and improve the prognosis.