ObjectiveTo explore the effects of negative pressure wound therapy(NPWT) combined with silver ion hydrogel dressing in the treatment of diabetic foot ulcer.
MethodsOne hundred and one patients with diabetic foot ulcer were randomly divided into the silver ion hydrogel dressing group(group A), NPWT group(group B) and NPWT combined with silver ion hydrogel dressing(group C).The wound granulation growth integral, wound healing time, antibiotic use time, and time and cost of each change were compared among three groups.
ResultsThe wound healing time in group A, B and C gradually shortened(P < 0.05 to P < 0.01).The duration of antibiotic use in group C was shorter than that in group A and group B(P < 0.05 to P < 0.01), and the difference of which between group A and group B was not statistically significant(P>0.05).The differences of granulation growth integral among three groups at the first week were not statistically significant(P>0.05), the differences of granulation growth integral between group A and group B, and between group B and group C at the second and third week were not statistically significant(P>0.05), and the granulation growth integral in group C was lower than that in group A(P < 0.05 to P < 0.01).The time and number of dressing change in group B and group C were significantly lower than those in group A(P < 0.01), and the difference of which between group B and group C was not statistically significant(P>0.05).The differences of the cost of dressing change between group A and group B, and between group B and group C were not statistically significant(P>0.05), and the cost of dressing change in group A was higher than that in group C(P < 0.05).
ConclusionsNPWT combined with silver ion hydrogel dressing can promote the growth of granulation tissue, shorten the healing time of diabetic foot ulcer wound, reduce the use time of antibiotics, and do not increase the workload of medical staff and treatment cost.
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