Application value of sufentanil combined with ropivacaine in the second cesarean section

ObjectiveTo observe the effects of sufentanil combined with ropivacaine on epidural anesthesia in the second cesarean section, and its influence on fetus.

MethodsForty puerperas with the second cesarean section were randomly divided into the sufentanil-ropivacaine group(group S) and ropivacaine group(group R)(20 cases each group).The mixture of 10 mL of 0.75% ropivacaine with 10 μg of sufentanil was injected into the epidural space in group S, and the 10 mL of 0.75% ropivacaine was injected into the epidural space in group R.The onset time of anesthesia, duration of analgesia, adverse reactions of anesthesia, and Apgar scores of neonates after 1 and 5 min of birth between two groups were compared.The blood gas analysis of umbilical vein and artery was performed at newborn birth, and the oxygen saturation(SpO₂) of right radial artery was compared among at 1, 2, 3, 4 and 5 min after birth.

ResultsThe onset time of anesthesia, duration of analgesia and anesthetic effect in group S were significantly shorter, longer and better than those in group R, respectively(P < 0.01 or P < 0.05).The difference of the adverse reaction of anaesthesia between two groups was not statistically significant(P>0.05).The differences of the Apgar scores of neonates after 1 and 5 min of birth, and SpO₂ of right radial artery at 1, 2, 3, 4 and 5 min after birth between two groups were not statistically significant(P>0.05).The differences of the indexes of blood gas analysis in umbilical vein and artery between two groups were not statistically significant(P>0.05).

ConclusionsThe application of sufentanil combined with ropivacaine in epidural anesthesia of puerpera with the second cesarean section can enhance the effects of anesthesia, improve the quality of anesthesia, and has no obvious effect on fetal respiratory oxygenation.