Effect of immunoglobulin on the clinical manifestation, percutaneous oxygen saturation and IgG level of neonates with infective pneumonia

ObjectiveTo analyze the effects of immunoglobulin therapy on the clinical manifestation, percutaneous oxygen saturation and IgG level of neonates with infective pneumonia.

MethodsA total of 86 neonates with infectious pneumonia were randomly divided into the control group and combined group(43 cases in each group).The control group and combined group were treated with the routine method and routine method combined with immunoglobulin.The clinical effect, clinical symptom improvement, percutaneous oxygen saturation and IgG level were compared between two groups.

ResultsThe total effective rate in combined group(95.35%) was higher than that in control group(76.74%)(P < 0.05).After treatment, the sputum suction times, cough relief time, pyretolysis time, disappearance time of shortness of breath, time of moist rale in lung and time of hospitalization in combined group significantly reduced compared with control group(P < 0.01).After treatment, the percutaneous oxygen saturation and IgG level in two groups were significantly higher than those before treatment, and which in combined group was significantly higher than that in control group(P < 0.01).

ConclusionsOn the basis of the routine treatment, the immunoglobulin therapy in neonatal infectious pneumonia can effectively improve the clinical symptoms, reduce the symptom disappearance or improvement time, improve the immune function, and has better effect.