ObjectiveTo explore the application value of closed-loop target control system to activate precise anesthesia in painless enteroscopy.
MethodsForty patients scheduled by painless enteroscopy, ASA Ⅰ-Ⅱ, aged 60-75 years, 22 males and 18 females, were randomly divided into the observation group(group S) and control group(group D) (20 cases in each group).The group S was treated with closed-loop target-controlled infusion of propofol with a target-controlled plasma concentration for 6μg/mL and BIS value for (55±5).The group D was treated with intravenous injection of propofol with 2 to 3 mg/kg.The HR, MAP, SpO2, BIS values, recovery time, propofol dosage during operation, departure score after sedation/anesthesia and perioperative adverse reactions were observed and compared between two groups.
ResultsAfter anesthesia, the levels of MAP and HR in two groups decreased(P < 0.01), the BIS value in group S decreased(P < 0.01), and was stable at about 55.Compared with the group S, the MAP decreasing and HR slowering in group D were more obvious in group S(P < 0.01).The SpO2 in group D decreased after anesthesia(P < 0.01), and which was lower than that in group S(P < 0.01).The propofol dosage and recovery time in group S were significantly lower than those in group D(P < 0.01).There was not statistical significance in departure score after sedation/anesthesia between two groups(P>0.01). There was not statistical significance in the incidence rate of perioperative adverse reactions between two groups(P>0.01).
ConclusionsThe application of closed-loop target control system in precise anesthesia during painless enteroscopy can significantly reduce the dosage of propofol, shorten the recovery time, maintain the stabliation of intraoperative circulation and respiratory function, and make patients more comfortable after operation.It is a safe and effective method of painless enteroscopy anesthesia, and worthy of promotion.
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