Comparison of the differences of postoperative lymph node positive gastric cancer patients treated with two kinds of intensity-modulated radiotherapy combined with chemotherapy

ObjectiveTo investigate the differences of therapeutic effects and adverse reactions between two kinds of intensity-modulated radiotherapy(IMRT) combined with chemotherapy in treating postoperative lymph node-positive gastric cancer.

MethodsTwenty-nine patients with postoperative lymph node-positive gastric cancer were treated with two kinds ofIMRTcombined with chemotherapy, and the differences of therapeutic effects and adverse reactions between two kinds of methods were compared.

ResultsThere is no difference in the effecacy between 5 fietd IMRT with 5 fields combined with chemotherapy and 9 fields combined with chemotherapy(P>0.05).The incidence rates of the nausea, vomiting and neutropenia of static IMRT with 5 fields were significantly higher than those of 9 fields(P < 0.01).After chemoradiotherapy, the chemotherapeutic tolerance of patients treated with static IMRT with 5 fields was significantly lower than that of static IMRT with 9 fields(P < 0.05).

ConclusionsDuring IMRT for patients with gastric cancer, the 9-field irradiation should be selected as far as possible after considering the influencing factors.