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    SHAN Hong-jie, XIAO Ying-li, MA Can, XIE Chang-hua, FENG Yang, XIA Yan. Value of tumor-stroma ratio in the prediction of the prognosis of breast cancer[J]. Journal of Bengbu Medical University, 2019, 44(12): 1631-1633. DOI: 10.13898/j.cnki.issn.1000-2200.2019.12.015
    Citation: SHAN Hong-jie, XIAO Ying-li, MA Can, XIE Chang-hua, FENG Yang, XIA Yan. Value of tumor-stroma ratio in the prediction of the prognosis of breast cancer[J]. Journal of Bengbu Medical University, 2019, 44(12): 1631-1633. DOI: 10.13898/j.cnki.issn.1000-2200.2019.12.015
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    Value of tumor-stroma ratio in the prediction of the prognosis of breast cancer

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      • Abstract
    • ObjectiveTo explore the value of tumor-stroma ratio(TSR) in the assessment of the prognosis of breast cancer, and its correlation with clinicopathology.
      MethodsOne hundred and twenty tumor tissue samples of breast cancer patients were stained using HE, the tumor cells in three visual fields with obvious tumor infiltration were calculated to obtain the highest value under the microscope.All cases were followed up, and the relationship between TSR, and clinicopathology and prognosis of breast cancer were analyzed.
      ResultsThe TSR was correlated with the lymph node metastasis and histological grade(P < 0.01).The single and multivariate analysis of prognosis showed that the TSR was an independent prognostic factor of breast cancer(P < 0.01).
      ConclusionsThe TSR is an independent prognostic factor of breast cancer, which has high repeatability and simple operation, and is worthy of clinical promotion.
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