Application value of ¹⁸F-FDG PET/CT in patients with suspected recurrence and metastasis after cervical cancer surgery

ObjectiveTo investigate the application value of ¹⁸F-FDG PET/CT in patients with suspected recurrence and metastasis after cervical cancer surgery.

MethodsThe clinical data of 56 female patients with suspected recurrence and metastasis of cervical cancer were collected.All patients were detected using ¹⁸F-FDG PET/CT whole-body imaging, and the results were determined by semi-quantitative analysis and visual examination.

ResultsAmong 56 patients, the recurrence and/or metastasis in 50 patients were found.The SUVmax of local recurrence focus ranged from 3.45 to 18.69, with an average SUVmax of 8.96.The sensitivity, specificity, diagnostic accuracy, positive predictive value and negative predictive value of ¹⁸F-FDG PET/CT in the diagnosis of recurrence and metastasis of cervical cancer after operation were 98.0%, 83.3%, 92.1%, 96.0% and 80.0%, respectively.The sensitivity, specificity, diagnostic accuracy, positive predictive value and negative predictive value of CT were 69.7%, 78.9%, 73.2%, 86.7% and 57.6%, respectively.The differences of the sensitivity, negative predictive value and diagnostic accuracy between two methods were statistically significant (P < 0.05).The results of ¹⁸F-FDG PET/CT imaging diagnosis were consistent with the histopathological or clinical following-up results.

ConclusionsThe ¹⁸F-FDG PET/CT imaging has important clinical practical value for suspected recurrence and metastasis of cervical cancer after operation, and can provide the important information for making correct treatment plan.