Analysis of the clinical characteristics and influencing factors of short-term prognosis in 67 patients with ASMVT

ObjectiveTo analyze the clinical characteristics and influencing factors of short-term prognosis in 67 patients with acute superior mesenteric venous thrombosis(ASMVT) for providing the reference in improving the prognosis of patients.

MethodsThe baseline data of 67 patients with ASMVT in our hospital from 2004 to 2016 were retrospectively analyzed.The clinical features among the patients with different treatment methods and lesion locations were compared.The patients were divided into the survival group and death group according to the prognosis, and the prognostic factors were analyzed using the univariate and multivariate logistic regression method.

ResultsAmong 67 cases with ASMVT, 8 cases died, and 59 cases survived.The ratios of peritoneal irritation, laparotomy and intestinal necrosis in isolated ASMVT group were significantly higher than that in combined ASMVT group(P < 0.05 to P < 0.01).The ratios of splenectomy in isolated ASMVT group were lower than that in combined ASMVT group(P < 0.05).The ratios of isolated ASMVT and death in open surgery group were significantly higher than those in interventional therapy group(P < 0.01).The time from onset to treatment of interventional therapy group was significantly higher than that in open surgery group and conservative treatment group(P < 0.05 to P < 0.01).The splenectomy, liver cirrhosis, hypersplenism, severe pancreatitis, venous thrombosis history, time from onset to treatment, duration of anticoagulant therapy less than 6 months, lesion location and intestinal necrosis could obviously affect the prognosis of patients with ASMVT(P < 0.05 to P < 0.01).The splenectomy, liver cirrhosis, hypersplenism, severe pancreatitis and duration of anticoagulant therapy less than 6 months were the independent risk factors of death in patients with ASMVT(P < 0.05 to P < 0.01).

ConclusionsThe combined ASMVT is easy to be found after splenectomy, and the ratio of open surgery, intestinal necrosis and higher peritoneal irritation in isolated ASMVT patients are high.The splenectomy, liver cirrhosis, hypersplenism, severe pancreatitis and duration of anticoagulant therapy less than 6 months are the main influencing factors of prognosis in patients with ASMVT.