Effects of different fluid restriction resuscitation on coagulation function and thromboelasticdiagram in patients with hemorrhagic shock

ObjectiveTo explore the rescue effect of different restrictive fluid resuscitation on traumatic hemorrhagic shock patients (HS) and the effects on coagulation function (prothrombin time, activated partial thrombin time) and thromboelastic diagram (K, R, MA, etc.).

MethodsForty HS patients were randomly divided into sodium acetate linge fluid group(AR group) and sodium lactate linge fluid group(LR group), with 20 cases in each group.AR group recovery liquid using sodium acetate ringer's solution, LR group recovery liquid using sodium lactate ringer's solution, adopt restrictive liquid recovery, recovery method respectively and recovery for 1 hour prior to the recovery after extracting peripheral venous blood samples, by comparing the two groups of patients with peripheral blood coagulation function and thrombus elastic figure, to observe the recovery effect of two kinds of liquid.

ResultsBefore the onset of resuscitation, there was no statistically significant difference between the two groups in peripheral blood clotting function and thromboelastic diagram (P>0.05).One hour after resuscitation, compared with the LR group, there were statistically significant differences in parameters related to thrombin time and kinetics time in the AR group(P < 0.05).

ConclusionsCompared with sodium lactate ringer's solution, sodium acetate ringer's solution for resuscitation of HS patients can better control the coagulation function of patients and related parameters of thromboelastic diagram, so that the liquid resuscitation of HS patients can achieve curative effect in the early stage.