ObjectiveTo observe the effects of the cognitive behavioral intervention and muscle relaxation training on psychological stress level and well-being in patients treated with in-vitro fertilization and embryo transfer(IVF-ET).
MethodsOne hundred and sixteen patients treated with IVF-ET from May 2017to July 2018 were were divided into the observation group and control group by random number table method(58 cases in each group).The control group was treated and nursed with routine method after admission.The observation group was treated with cognitive behavioral intervention and muscle relaxation training on the basis of the control group.Before and after treatment(completing embryo transfer), the anxiety and depression, and sleep condition in two groups were evaluated using self-rating anxiety scale(SAS) and self-rating depression scale(SDS), and self-rating scale of sleep(SRSS), respectively.The serum levels of cortisol in two groups were detected using chemiluminescent immunoassay.The well-being in two groups after treatment were assessed using Memorial University of Newfoudland Scale of Happiness(MUNSH), and the pregnancy in two groups after 1 month of treatment were identified using ultrasound examination.
ResultsBefore treatment, the differences of the scores of SDS and SAS were not statistically significant between two groups(P>0.05).After treatment, the scores of SDS and SAS in two groups were significantly lower than those before intervention, and the SDS and SAS scores in observation group were significantly lower than those in control group(P < 0.01).Before treatment, the difference of the sleep quality score was not statistically significant between two groups(P>0.05).After treatment, the sleep quality in observation group was significantly better than that in control group(P < 0.01).Before treatment, the difference of the cortisol level was not statistically significant between two groups(P>0.05).After treatment, the cortisol level in observation group was significantly lower than that in control group(P < 0.01).The pregnancy rate in observation group was higher than that in control group(P < 0.05).The negative score of the MUNSH scale in observation group was significantly lower than that in control group, and the positive score and total score in obseravtion group were significantly higher than those in control group(P < 0.01).
ConclusionsThe cognitive behavioral intervention combined with muscle relaxation training can effectively alleviate anxiety and depression, improve sleep quality and well-being, reduce psychological stress and improve pregnancy success rate in patients treated with IVF-ET.
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