Efficacy of the intrathecal injection of methylprednisolone in the rehabilitation of incomplete spinal cord injury

ObjectiveTo observe the effects of intrathecal injection of methylprednisolone in the rehabilitation of incomplete spinal cord injury.

MethodsOne hundred and thirty-one incomplete paraplegia patients with spinal cord injury were randomly divided into the observation group(68 cases) and control group(63 cases).Two groups were treated with the common rehabilitation method, and the observation group was additionally treated with intrathecal injection of methylprednisolone.Two groups were evaluated before and after treatment according to the American Spinal Injury Association(ASIA) criteria.

ResultsThere was no statistical significance in ASIA score between two groups before treatment(P>0.05).After 8 weeks of treatment, the ASIA scores in two groups were significantly higher than that before treatment(P＜0.01), and the scores in observation group were significantly higher than those in the control group(P＜0.01).

ConclusionsThe intrathecal injection of methylprednisolone can significantly improve the postoperative rehabilitation effects in patients with spinal cord injury.