Application value of nano carbon tracing sentinel lymph node detection technique in laparoscopic surgery of early endometrial cancer

ObjectiveTo investigate the clinical value of nano carbon tracing sentinel lymph node(SLN) in laparoscopic surgery for early endometrial cancer.

MethodsForty patients with early endometrial cancer were treated with laparoscopic double appendages combined with pelvic and/or paraaortic lymphadenectomy.During the operation, the SLN were identified using nano carbon tracer, and the detection of black stained SLN was recorded.The pathological examination of the removed lymph nodes after the operation was performed.

ResultsAmong 40 patients, 142 black stained lymph nodes in 37 cases were detected, with an average of 3.8 per patient, and the detection rate was 92.5%.There was no statistical significance in the SLN detection rate of different injection sites, phases and tumor diameters(P>0.05).The SLN of endometrial carcinoma was mainly distributed in external iliac lymph nodes(32.4%, 46/142) and obturator lymph nodes(25.7%, 37/142).The sensitivity of nano carbon tracing SLN was 100%, and the negative predictive value was 100%.

ConclusionsThe technique of nano carbon tracing SLN in early endometrial carcinoma under laparoscopy is feasible, which provides an effective basis for the determination of lymph node metastasis and selection of surgical scope.