Effect of oxycodone combined with ropivacaine in the transverse abdominal fascia plane block on the ehanced recovery after surgery after abdominal surgery

ObjectiveTo investigate the effects of oxycodone combined with ropivacaine in the transverse abdominal fascia plane block(TAPB) on the enhanced recovery after abdominal surgery.

MethodsNinety patients with abdominal gastrointestinal tumors, aged 35 to 69 years, body mass index < 30 kg/m² and ASA grade Ⅰ to Ⅱ, were treated with open surgery, and the patients were divided into the observation group and control group(45 cases in each group).The control group was treated with oxycodone intravenously combined with ropivacaine incision, and the observation group was treated with oxycodone intravenously combined with TAPB.The pain scores, sedation scores, postoperative complications, anal exhaustion time, first feeding time, getting out of bed time and length of hospital stay was recorded in two groups at the time of leaving operating room, and postoperative 6 h, 12 h and 24 h.

ResultsThe VAS scores of the resting after 6 h and 12 h of operation and exercise after 6 h, 12 h and 24 h of operation in observation group were significantly lower than those in control group(P < 0.01).The differences of the sedation scores at each time-point between two groups were not statistically significant(P>0.05).The anal exhaust time, first drinking water time and get out of bed time in observation group were significantly shorter than those in control group(P < 0.01).The incidence rate of postoperative anesthesia-related complications in observation group was few compared with that in control group, but the difference of which was not statistically significant(P>0.05).

ConclusionsThe oxycodone combined with TAPB can improve the postoperative analgesic effects and improve the gastrointestinal function, reduce the incidence rate of postoperative complications and accelerate the postoperative recovery of patients.