Analysis of the influencing factors of radiation gastritis induced by intensity-modulated radiotherapy after esophageal cancer operation

ObjectiveTo analyze the related factors of acute radiation gastritis induced by intensity-modulated radiotherapy after esophageal cancer surgery.

MethodsThe maximum dose(Dmax), mean dose(Dmean), intrathoracic stomach volume in different locations, illuminated volume percent(V5, V10, V20, V30, V40, V45 and V50), intrathoracic stomach illuminated volume(aV5, aV10, aV20, aV30, aV40 aV45 and aV50) in 60 esophageal cancer patients treated with postoperative intensity modulated cancer radiotherapy were calculated using the dose volume histogram.The differences of intrathoracic stomach volume in different locations were analyzed.The optimal critical value was determined by ROC curve, and the predictive index was determined by logistic multivariate analysis.

ResultsThe differences of the intrathoracic stomach volume between the right side and left side, mediastinum were statistically significant(P < 0.05).The V50 and aV50 were the indicator to predict acute radioation gastritis(P < 0.01).

ConclusionsIn the evaluation of postoperative induced by intensity-modulated radiotherapy plan for esophageal cancer, the evaluation of V50 and aV50 in pleural and gastric areas should be greatly focused on.