XU Feng, WANG Yi-qiao, LI Zha-bing, QI Yi-bao, BAO Qing-song, ZHANG Xiao-long. Comparison of the analgesia effects between magnesium sulfate or dexmedetomidine combined with ropivacaine in superficial cervical plexus block after cochlear implantation[J]. Journal of Bengbu Medical University, 2020, 45(8): 1024-1028. DOI: 10.13898/j.cnki.issn.1000-2200.2020.08.009
    Citation: XU Feng, WANG Yi-qiao, LI Zha-bing, QI Yi-bao, BAO Qing-song, ZHANG Xiao-long. Comparison of the analgesia effects between magnesium sulfate or dexmedetomidine combined with ropivacaine in superficial cervical plexus block after cochlear implantation[J]. Journal of Bengbu Medical University, 2020, 45(8): 1024-1028. DOI: 10.13898/j.cnki.issn.1000-2200.2020.08.009

    Comparison of the analgesia effects between magnesium sulfate or dexmedetomidine combined with ropivacaine in superficial cervical plexus block after cochlear implantation

    • ObjectiveTo evaluate the analgesia effects between magnesium sulfate or dexmedetomidine combined with ropivacaine in superficial cervical plexus block after cochlear implantation.
      MethodsEighty-eight patients scheduled by cochlear implantation were randomly divided into the group R(29 cases), group RD(29 cases) and group RM(30 cases) according to digital table
      method.The superficial cervical plexus block in group R was implemented using 13 mL of 0.25% ropivacaine combined with 2 mL of 0.9% sodium chloride solution, the superficial cervical plexus block in group RD was implemented using 13 mL of 0.25% ropivacaine combined with 0.75 mg/kg dexmedetomidine diluted to 2 mL, and the superficial cervical plexus block in group RM was implemented using 13 mL of 0.25% ropivacaine combined with 4 mg/kg magnesium sulfate diluted to 2 mL.Three groups were treated with static aspiration combined general anesthesia.The VAS scores in three groups after 1, 6, 12, 18 and 24 h of operation were recorded.The Ricker sedation-agitation score in the wake period during extubation, time of the first remedial analgesia, dosage of the remedial analgesia drugs, incidence rate of perioperative adverse reactions and satisfaction scores of patients among three groups were compared.
      ResultsThe differences of the VAS scores among three groups after 1, 6 and 24 h of operation were not statistically significant(P>0.05), the VAS scores in group RM and group RD after 12 h of operation were lower than those in group R, and the VAS score in group RD after 12 h of operation was lower than that in group RM and group R(P < 0.05).The Ricker sedation-agitation scores in group R, group RD and group RM during extubation gradually decreased, the time of the first remedial analgesia in group RD and group RM prolonged compared with group R, the dosage of the remedial analgesia drugs in group R, group RD and group RM gradually decreased, and the satisfaction score in group R was lower than that in group RD and group RM(P < 0.05 to P < 0.01).There was no statistical significance in the vomiting rate among three groups(P>0.05).The incidence rate of bradycardia in group RD was higher than that in group R and group RM(P < 0.05).
      ConclusionsBoth magnesium sulfate and dexmedetomidine combined with ropivacaine ultrasonic-guided superficial cervical plexus block can prolong the duration of postoperative analgesia, reduce the use of intravenous analgesia drugs and incidence rate of agitation during anaesthesia recovery, and improve satisfaction in patients treated with cochlear implantion.Compared with magnesium sulfate, the duration of postoperative analgesia is relatively long, and the agitationnd postoperative bradycardia rate are high in patients treated with dexmedetomidine.
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