Application value of ¹⁸F-FDG PET/CT in the detection of metastasis or recurrence of ovarian cancer patients with CA125 increasing after operation

ObjectiveTo explore the value of ¹⁸F-FDG PET/CT in detecting the metastasis or recurrence of ovarian cancer patients with serum CA125 increasing after surgery.

MethodsThe clinical data of 32 suspected metastasis or recurrence ovarian cancer patients with postoperative CA125 level increasing were retrospectively analyzed.The results of 18F-FDG PET/CT were compared with traditional imaging(CT or ultrasound).The diagnosis results of patients were confirmed by the pathological examination of reoperation or puncture biopsy, and following-up data of clinical and imaging data.

ResultsThe results of 18F-FDG PET/CT showed that the common sites of metastasis or recurrence were pelvis, abdominal cavity and thorax in turn, and the metastasis organs included the lymph node, lung, liver, spleen and bone.The SUVmax value of metastatic or recurrent lesions was higher than the normal reference value.The sensitivity and accuracy of 18F-FDG PET/CT were higher than those of traditional imaging(P < 0.05 and P < 0.01), but the difference of the specificity between two methods was not statistically significant(P>0.05).

Conclusions18F-FDG PET/CT has a high diagnostic efficacy in the metastasis or recurrence of ovarian cancer after operation.