Comparison of short-term efficacy of laparoscopy therapy in elderly patients with advanced gastric cancer

ObjectiveTo analyze the clinical efficacy and safety of total laparoscopic radical gastrectomy and laparoscope-assisted radical gastrectomy in elderly patients with advanced gastric cancer, to provide reference for the surgical treatment of elderly patients with gastric cancer.

MethodsA total of 54 elderly patients with advanced gastric cancer were selected and divided into total laparoscopic radical gastrectomy group (n=24) and laparoscope-assisted radical gastrectomy group (n=30) according to random number table method.The blood loss, number of lymph node dissection, postoperative pain score, exhaust time, eating time, hospitalization time, complication rate, C-reactive protein (CRP), CD4/CD8 and patient's satisfaction were compared between the two groups.

ResultsThere were significant differences in postoperative pain score, exhaust time and hospitalization time between the two groups (P < 0.01).The level of CRP at 3 d and 7 d after operation in total laparoscopic radical gastrectomy group was significantly lower than that in laparoscope-assisted radical gastrectomy group (P < 0.01), and the level of CD4/CD8 at 1 d and 7 d after operation was higher than that in laparoscope-assisted radical gastrectomy group (P < 0.01 and P < 0.05), which at 1 d after operation was significantly higher than that before operation (P < 0.01).

ConclusionsThe total laparoscopic radical gastrectomy has obvious advantages in short-term clinical efficacy for elderly patients with advanced gastric cancer.