Study on the correlation between ambulatory blood pressure parameters and severity of coronary lesion

ObjectiveTo study the correlation between ambulatory blood pressure parameters and severity of coronary lesion.

MethodsThe 24 h ambulatory blood pressure and coronary angiography in 322 patients suspected by coronary heart disease were detected.According to the results of coronary angiography, the patients were divided into the normal coronary artery group(85 cases) and single vessel lesion group(91 cases), two branches lesion group(77 cases) and three branches lesion group(69 cases).The ambulatory blood pressure parameters were compared among 4 groups.

ResultsThe 24-h ASBP, 24-h APP, dAPP, nASBP and nAPP in patients with single, double and three-vessel lesions were significantly higher than those in patients with normal coronary artery(P < 0.05 to P < 0.01).The number of lesion branches(double and three branches) in non-dipper, reverse dipper and super-dipper blood pressure patterns patients were higher than those in dipper blood pressure patterns patients(P < 0.01).Under the arytenoid blood pressure pattern, the proportional distribution of normal, single, double and three branches lesion gradually decreased(P < 0.01).Under the inverting arytenoid blood pressure pattern, the proportional distribution of three, double, single and normal branches lesion gradually decreased(P < 0.01).The results of multiple logistic regression analysis showed that the smoking, diabetes, 24 hASBP, dASBP, 24 hAPP, dAPP, and nAPP were the risk factors for coronary heart disease(P < 0.05 to P < 0.01).

ConclusionsThe ambulatory blood pressure pattern is significantly correlated with the severity of hypertensive target organ damage.