Clinical application value of grip strength measurement in the assessment of nutritional status of patients with cirrhosis

ObjectiveTo explore the application value of grip strength(GS) measurement in the assessment of nutritional status of patients with cirrhosis.

MethodsThe nutritional status of 76 patients with cirrhosis were assessed using MNA-SF.According to the MNA-SF score, the patients were divided into the normal nutrition group(n=21), malnutrition risk group(n=30) and malnutrition group(n=25).The anthropometric index, human component index, biochemical index and resting energy consumption in three groups were measured, and their correlation with GS were analyzed.

ResultsThe GS, MAC, AMC, CC, TSF and BMI in normal nutrition group were significantly higher than those in malnutrition risk group and malnutrition group(P < 0.01);and the GS, MAC, AMC, CC, TSF and BMI in malnutrition risk group were significantly higher than those in malnutrition group(P < 0.01).There was no statistical significance in the ICW, ECW and TBW among three groups(P>0.05).The ECW/TBW in normal nutrition group was significantly lower than that in malnutrition risk group and malnutrition group(P < 0.05), and the ECW/TBW in malnutrition risk group was significantly lower than that in malnutrition group(P < 0.01).In malnutrition risk group and malnutrition group, the REE Prre were significantly higher than REE Meal(P < 0.01), the REE Prre in malnutrition risk group and malnutrition group were significantly higher than that in normal group(P < 0.01), and the REE Prre in malnutrition group was significantly higher than that in malnutrition risk group(P < 0.01).The results of Pearson correlation analysis showed that GS was positively correlated with MAC, AMC, CC, BMI and ALB(P < 0.01), negatively correlated with TSF and REE Prre(P < 0.01), and not correlated with TRF, PA, Hb, FN, RBP and TLC(P>0.05).

ConclusionsGS is closely related to other nutritional indicators in patients with cirrhosis.Therefore, GS measurement can be used as a nutritional status assessment method in patients with cirrhosis, and it can be further popularized in clinical practice.