Appliance value of half-course renal artery blocking in laparoscopy partial nephrectomy

ObjectiveTo investigate the safety and protective effect on renal function of half-course renal artery blocking in laparoscopy partial nephrectomy(LPN).

MethodsThe clinical data of 94 stage T1 renal cancer patients treated with LPN were retrospectively analyzed.The patients were divided into the half-course renal artery blocking group(group A, 32 cases))and whole-course renal artery blocking group(group B, 62 cases)according to the blocking course of renal artery.According to the tumor staging, the group A was subdivided into the stage T1a group(group A1, 21 cases)and stage T1b group(group A2, 11 cases), and the group B was subdivided into the stage T1a group(group B1, 43 cases)and stage T1b group(group B2, 19 cases).The operation time(OT), bleeding volume(BV), warm ischemia time(WIT), hematuria and urine leakage of perioperative indicators, and renal atrophy and renal function loss of long-term complications parameters in group A and group B were analyzed.

ResultsThe operations in all patients were successfully completed.The WIT in group A was significant shorter that in group B, and the decreasing value of eGFR in group A was significant lower that in group B(P < 0.01).The WIT in group A1 and group A2 were shorter those in group B1 and group B2, respectively(P < 0.01).However, there was no statistical significance in OT, BV, hematuria, urine leakage, renal function decline and renal atrophy between group A and group B(P>0.05).

ConclusionsThe half-course renal artery blocking can shorten renal WIT and reduce incidence of postoperative renal atrophy, especially for patients with stage T1b renal tumor.It has good safety and practicability, and is worthy of clinical application and promotion.