Study on the ultrasound and clinical characteristics of primary parathyroid tumors

ObjectiveTo analyze the clinical features and ultrasonographic features of patients with parathyroid tumors, and provide the reference for the diagnosis and differential diagnosis of parathyroid tumors.

MethodsThe clinical data of 80 patients with parathyroid tumor treated with operation were retrospectively analyzed, The patients were divided into the adenoma group(69 cases with parathyroid adenom), cancer group(4 cases with parathyroid carcinoma) and cyst group(7 cases with parathyroid cyst).

ResultsThe kidney stones were the main clinical manifestations in adenoma group(9/69, 13.04%).The serum phosphorus levels in cyst group were higher than that in adenoma group and cancer group(P < 0.05), and the serum levels of alcium and alkaline phosphatase in adenoma group were higher than those in cyst group(P < 0.05).The differences of the accuracy of ultrasound localization among patients with different types of parathyroid tumors were statistically significant(P < 0.01), and which in adenoma was the highest79.71% (55/69).The differences of the vertical, transverse and anteroposterior diameters in patients with different types of parathyroid tumors were statistically significant(P < 0.01), and the vertical, transverse and anteroposterior diameters in adenoma group and cancer group were less than those in cyst group(P < 0.05).Fourteen patients in the parathyroid adenoma group were misdiagnosed, and the nodular goiter(5 cases) and thyroid adenoma(5 cases) were the most common.

ConclusionsIn the diagnosis of parathyroid adenoma, the clinical manifestations, blood phosphorus, ALP, other relevant indicators of laboratory examination and characteristics of ultrasonography should be taken into comprehensive consideration, , and the ⁹⁹Tcm-MIBI examination should be combined when necessary.