Clinical efficacy of laparoscopic myomectomy and its influence on hormone index and inflammatory factor level

ObjectiveTo investigate the clinical efficacy of laparoscopic myomectomy and its influence on hormone index and inflammatory factor level.

MethodsSeven hundred and twenty patients with uterine myoma were randomly divided into the control group and observation group(360 cases in each group).The control group was treated with traditional laparotomy, and the observation group was treated with laparoscopic myomectomy.The levels of inflammatory factors, stress hormones and ovarian function indexes before and after treatment were compared between two groups.

ResultsThe operative time, intraoperative blood loss, anal exhaust time, VAS score and length of hospital stay in observation group were significantly better than those in control group(P < 0.01).There was no statistical significance in the levels of TNF-α, CRP, COR, NE, LH, FSH, E2 between two groups before operation(P>0.05).The levels of TNF-α, CRP, COR, NE, LH and FSH in two groups after operation significantly increased with compared which before operation, and which in observation group were lower than those in control group(P < 0.01).The levels of E2 in two groups after operation significantly decreased compared with before operation, and which in observation group was significantly higher than that in control group(P < 0.01).

ConclusionsThe clinical efficacy of laparoscopic myomectomy is good, which can effectively reduce inflammation and stress reaction, alleviate immunosuppression, reduce serum trauma reaction and improve ovarian function.