Application value of the dexmedetomidine under SEDline sedation monitoring in patients treated with thoracoscopic lobectomy

ObjectiveTo evaluate the application value of dexmedetomidine under SEDline sedation monitoring in thoracoscopic lobectomy in order to provide a more safe and effective method for anesthesia.

MethodsA total of 20 ASA Ⅰ or Ⅱ patients treated with thoracoscopic lobectomy were randomly divided into the dexmedetomidine group(group D)and control group(group N)(10 cases in each group).The MAP, HR, SpO₂ and PSI in two groups before anesthesia induction(T₀), during skin incision(T₁), after 30 minutes of one lung ventilation(T₂)and immediately after surgery(T₃)were recorded.The dosage of remifentanil and propofol, and scores of VAS and Ramsay after 6 h and 24 h of operation were recorded.

ResultsThe MAP, HR and PSI in two groups at T₁, T₂ and T₃ decreased(P < 0.01), the decreasing degree of MAP in group N was more obvious compared with the group D at T₂(P < 0.01), the HR in group D at T₁was significantly lower than that in group N(P < 0.01), and the PSI in group D was lower than that in group N at T₂(P < 0.01).The dosage of remifentanil and propofol in group D were significantly lower than these in group N.The scores of VAS and Ramsay in group D were lower and higher than that in group N after 6 h of operation, respectively(P < 0.01).

ConclusionsThe dexmedetomidine under SEDline sedation monitoring in patients treated with thoracoscopic lobectomy can control the patient's anesthetic state, maintain the hemodynamics, improve the postoperative sedation and analgesia, and have no postoperative agitation, which can plays certain positive roles in the patient's quick recovery.